Pimelic Diphenylamide 106

CAS No. 937039-45-7

Pimelic Diphenylamide 106 ( RGFA-8;TC-H 106;BRD-4657 )

Catalog No. M16712 CAS No. 937039-45-7

A slow, tight-binding inhibitor of class I HDACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 38 In Stock
10MG 60 In Stock
25MG 104 In Stock
50MG 177 In Stock
100MG 323 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pimelic Diphenylamide 106
  • Note
    Research use only, not for human use.
  • Brief Description
    A slow, tight-binding inhibitor of class I HDACs.
  • Description
    A slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively); shows weak inhibition on HDAC8 (IC50=5 uM); has preference toward HDAC3.
  • Synonyms
    RGFA-8;TC-H 106;BRD-4657
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    937039-45-7
  • Formula Weight
    339.43
  • Molecular Formula
    C20H25N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 25 mg/mL
  • SMILES
    O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=C(C)C=C2)=O
  • Chemical Name
    Heptanediamide, N1-(2-aminophenyl)-N7-(4-methylphenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.
2. Xu C, et al. Chem Biol. 2009 Sep 25;16(9):980-9.
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